Bio Sketch
Personal Details:
Name | : | Dr. Jayesh Antony |
Department | : | Zoology |
Designation | : | Asst. Professor |
Address | : | Neerakkal House House , Muttuchira P.O. P.O , Kottayam , Kottayam , Kerala ,India - 686613 |
: | [email protected] , [email protected] |
Education:
Sl. No | Course | Institution | Period | Achievements |
---|---|---|---|---|
1 |
PhD in Biotechnology |
Rajiv Gandhi Centre for Biotechnology, Trivandrum [University of Kerala] |
July 2015 |
M R Das Career award, July 2015 |
2 |
M.Sc. Biotechnology |
St.Peter's College, Kolenchery-[Mahatma Gandhi University] |
2002- 2004 |
70.4% |
3 |
B.Sc. Zoology |
St.Xavier's College, Vaikom- [Mahatma Gandhi University] |
1999-2001 |
98.5% [M.G.University First Rank] |
4 |
Pre- degree |
Deva Matha College, Kuravilangadu- [Mahatma Gandhi University] |
1996-1998 |
72% |
5 |
S.S.L.C |
[St.Emmanuel's H.S.Kothanalloor-Kerala Board of Examinations] |
1996 |
76.8% |
Area of Specialization / Research Interests:
AREA OF SPECIALIZATION / RESEARCH INTERESTS |
---|
Cancer chemotherapy, chemosensitization, Bioprospecting |
Career Profile:
Sl.No | Name of the Institution | Designation | period |
---|---|---|---|
1 |
Rajiv Gandhi Centre for Biotechnology, Trivandrum |
PhD Scholar |
July 2008 to July 2015 |
2 |
Rajiv Gandhi Centre for Biotechnology, Trivandrum |
Junior Research Fellow |
January 2007 to June 2008 |
3 |
K.E. College, Mannanam, Kottayam |
Lecturer |
February 2006 to January 2007 |
4 |
C.M.S. College, Kottayam |
Lecturer |
July 2004 to July 2005 |
5 |
Rajiv Gandhi Centre for Biotechnology, Trivandrum |
Senior Research Fellow |
August 2015 to January 2016 |
6 |
Department of Zoology, St.Thomas College, Palai |
Assistant Professor |
27 January 2016 |
7 |
Department of Zoology, St.Thomas College, Palai |
Assistant Professor Stage II |
27 January 2020 |
Publications:
Research Publication:
Sl.No | Publication | Publication Year |
---|---|---|
1 |
Jayesh Antony,A Shabna,S. Sankar,Minakshi Saikia, Ruby John Anto Pharmacological attenuation of melanoma by tryptanthrin pertains to the suppression of MITF-M through MEK/ERK signaling axis. Cellular and Molecular Life Sciences 79:478 |
2022 |
2 |
Chitosan Encapsulation Enhances the Bioavailability and Tissue Retention of Curcumin and Improves its Efficacy in Preventing B[a]P-induced Lung Carcinogenesis.Vijayakurup V1, Thulasidasan AT1, Shankar G M1,2, Retnakumari AP1, Nandan CD3, Somaraj J1, Antony J1, Alex VV1, Vinod BS1, Liju VB1, Sundaram S4, Kumar GSV3, Anto RJ5.Cancer Prev Res (Phila). 2019 Apr;12(4):225-236. doi: 10.1158/1940-6207.CAPR-18-0437. Epub 2019 Feb 13. |
2019 |
3 |
Evaluation of uttroside B, a saponin from Solanum nigrum Linn, as a promising chemotherapeutic agent against hepatocellular carcinoma, Lekshmi R. Nath, Jaggaiah N. Gorantla, Arunkumar T. Thulasidasan,Vinod Vijayakurup, Shabna Shah, Shabna Anwer, Sophia M. Joseph, Jayesh Antony, Kollery Suresh Veena, Sankar Sundaram, Udaya K. Marelli, Ravi S. Lankalapalli and Ruby John Anto, Scientific Reports, October 2016 [Accepted] |
2016 |
4 |
miR cluster 143/145 directly targets Nrl and regulates rod photoreceptor development, Sreekumaran Sreekanth; Vazhanthodi A Rasheed, Ph.D.; Lalitha Soundararajan; Jayesh Antony, Ph.D.; Minakshi Saikia; Krishnankutty C Sivakumar; Ani V Das, PhD, Molecular Neurobiology, October 2016 [Accepted] |
2016 |
5 |
Antioxidant and cytotoxic effects of essential oil, water and ethanol extracts of major Indian spices Shamina Azeez*, Jayesh Antony**, N.K. Leela and Ruby John Anto** Indian J. Hort. 73(2), June 2016: 229-237DOI : 10.5958/0974-0112.2016.00053.0 |
2016 |
6 |
Lekshmi R. Nath, Jaggaiah N. Gorantla, Sophia Margaret Joseph, Jayesh Antony, Sanu Thankachan, Darsan B. Menon, S. Sankar, Ravi S. Lankalapalli and Ruby John Anto. Kaempferide, the most active among the four flavonoids isolated and characterized from Chromolaena odorata, induces apoptosis in cervical cancer cells while being pharmacologically safe. RSC Adv., 2015,5, 100912-100922, DOI: 10.1039/C5RA19199H |
2015 |
7 |
Vineshkumar T. Puliyappadamba, Arun Kumar T Thulasidasan, V Vinod, Jayesh Antony, Smitha V. Bava, A Shabna, S Sankar and Ruby John Anto. Curcumin inhibits B[a]PDE-induced procarcinogenic signals in lung cancer cells, and curbs B[a]P-induced mutagenesis and lung carcinogenesis. Biofactors 2015 Dec 8. doi: 10.1002/biof.1244 |
2015 |
8 |
Jayesh Antony, Minakshi Saikia, Vino T. Cheriyan, Nishanth Kumar S and Ruby John Anto. Sesbania: A Prospective Candidate to be Excavated for Anticancer Drugs. The Natural Products Journal, 5(4): 273-287. DOI: 10.2174/1872211310999151110155644 (2015). |
2015 |
9 |
Antony, J. et al. DW-F5: A novel formulation against malignant melanoma from Wrightia tinctoria. Sci. Rep. 5, 11107; doi: 10.1038/srep11107 (2015) |
2015 |
10 |
BS Vinod, *J Antony, HH Nair, VT Puliyappadamba, M Saikia, S Shyam Narayanan, A Bevin and R John Anto. Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil. Cell Death and Disease 2013 February; 4(2): e505. Published online 2013 February 21. doi: 10.1038/cddis.2013.26 (*Sharing Equal First authorship) |
2013 |
11 |
Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia, Ruby John Anto, Curcumin sensitizes breast cancer cells to 5-FU through thymidylate synthase- dependent downregulation of NF-κB (Abstract). Journal of Carcinogenesis, Vol.11, Supplement 1, 2012, pp-S31 |
2012 |
12 |
M. S. R. Murty, B. Ramalingeswara Rao, Kesur R. Ram, J. S. Yadav, Jayesh Antony and Ruby John Anto, Synthesis and preliminary evaluation activity studies of novel 4- (aryl/heteroaryl-2-ylmethyl) 6-phenyl-2-[3-(4-substitutedpiperazine-1-yl)propyl] pyridazin-3(2H)- one derivatives as anticancer agents. Medicinal Chemistry Research. October 2012, Volume 21, Issue 10, pp 3161-3169. |
2012 |
13 |
Jayesh Antony and Ruby John Anto. A molecular approach to Skin Cancer. Amala Research Bulletin 28 (2008), Pp141-152 |
2008 |
14 |
Parry Varghese., Rojimon. P. Thomas., Jayesh Antony.,Simimol Cyriac.,Rajasekharan. and Manuel Thomas. Bacterial pathogens associated with liquid wastes in a nosocomial environment. Proce. Of Ind. Env. Congress, 2006. Amritha Vishwa Vidyapeedam |
2006 |
15 |
Manuel Thomas., Rojimon. P. Thomas., Jayesh Antony., K. Rajasekharan. and Raja.M.P. A study on microbial contamination in domestic environment.S.B.Academic Review.Vol-XIII.Part-1.Pp.63-66 |
2006 |
Books:
Sl.No | Name of the Book | Year of publication | Name of Publisher | ISBN No | Nature of Contribution |
---|---|---|---|---|---|
1 |
The Enzymes, Volume 37, 2015 |
2015 |
Elsevier |
1874-6047 |
Jayesh Antony • G. Mohan Shankar • Ruby John Anto . Quercetin and Tryptanthrin: Two Broad Spectrum Anticancer Agents for Future Chemotherapeutic Interventions, Pages 43–72, Chapter 2. |
2 |
Anticancer properties of fruits and vegetables: A scientific review |
2014 |
World Scientific Publishing Co |
978-981-4508-88-9 |
*Jayesh Antony, *Minakshi Saikia and Ruby John Anto. Phytochemicals from Fruits and Vegetables as potential anti-cancer agents: special reference to skin cancer, Chapter, pp 277-307 |
3 |
Pandemics and Global Health |
2021 |
Nova Science Publishers, USA |
978-1-68507-261-2 |
Chapter 4. The Role of Vaccines in Public Health |
Details of Workshops/ Conferences/ Seminars/ Symposia Attended/ Papers Presented / Talks Given:
Sl. No |
Title of the seminar/ conference etc. |
Invited / Contributed /Partic-ipation |
Venue/ Agency |
Dates | Inter-national/ National/ Regional |
Title of the Paper |
---|---|---|---|---|---|---|
1 |
26th Kerala Science Congress |
Contributed |
Wayanad, Kerala |
28-31 January 2014 |
National |
Identification and characterization of Tryptanthrin, the active principle from Wrightia tinctoria and the validation of its anticancer efficacy in vitro and in vivo. Jayesh Antony, Minakshi Saikia And Ruby John Anto, Cancer Research Program, Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram-695014 |
2 |
RGCB Merit Award-2013 |
Contributed |
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram-695014 |
November, 2013 |
Regional |
Molecular Evaluation of Anticancer Properties of the Active Principle/s from the Indegenous Medicinal Plant Wrightia tinctoria. Jayesh Antony and Ruby John Anto. |
3 |
33rd Annual convension of Indian Association for Cancer Research Discovery, Innovation and Translation in Cancer Research |
Contributed |
Kollam, Kerala |
February 13-15, 2014 |
National |
Jayesh Antony, Minakshi Saiki, Sophia Margeret Joseph, Vinod.V., Lekshmi. R. Nath, Mohana Rao Katiki, M.S.R. Murty and Ruby John Anto. In vitro and in vivo validation of anticancer efficacy of tryptanthrin, isolated from Wrightia tinctoria [Roxb.] R.Br. |
4 |
3rd International Conference [Carcinogenesis 2012] on frontiers in carcinogenesis and preventive oncology: molecular mechanisms to therapeutics |
Contributed |
New Delhi, India |
November 19-21, 2012 |
International |
Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia, Ruby John Anto, Curcumin sensitizes breast cancer cells to 5-FU through thymidylate synthase- dependent downregulation of NF-κB |
5 |
International Conference on Advances in Biological Sciences |
Contributed |
Kannur University |
March 2012 |
International |
Jayesh Antony, Sophia Margeret Joseph, Lekshmi. R. Nath, Harsha Chandran and Ruby John Anto. Isolation, identification and molecular characterization of a potential anticancer compound Wrightiadione from the indigenous medicinal plant, Wrightia tinctoria. |
6 |
Indian Academy of Cancer research Satellite Meeting |
Participation |
Amala Cancer Research Centre, Trichur |
February 2011 |
National |
Jayesh Antony, Sophia Margeret Joseph, Lekshmi. R. Nath, Harsha Chandran and Ruby John Anto. A study on the anticancer properties of the active principle/s from indigenous medicinal plant Wrightia tinctoria [Roxb.] R. Br. |
7 |
International Cancer Research Sympossium |
Contributed |
Rajiv Gandhi Centre for Biotechnology, Trivandrum |
December 2010 |
International |
Jayesh Antony, Sophia Margeret Joseph, Lekshmi. R. Nath, Harsha Chandran and Ruby John Anto. A study on the anticancer properties of the active principle/s from indigenous medicinal plant Wrightia tinctoria [Roxb.] R. Br. |
8 |
International Conference of Science and Technology |
Participation |
S.B.College,Changanacherry |
2005 |
International |
A comparative study on the antimicrobial effect of selected oils. |
9 |
International Conference of Science and Technology |
Participation |
S.B.College, Changanacherry |
2005 |
International |
Jayesh Antony and Deepa Alex. A study on extraction of metabolites from fungi. |
10 |
International Conference of Science and Technology |
Participation |
S.B. College, Changanacherry |
2005 |
International |
Jayesh Antony and Rakesh Kumar T. Pollution in bottled water- An appraisal. |
11 |
International Conference on Neutraceuticals |
Participation |
Cochin, Kerala, India |
9-11 September 2016 |
International |
Evaluation of Tryptanthrin as an effective chemosensitizer for Dacarbazine chemotherapy against malignant melanoma, Minakshi Saikia, Jayesh Antony, Shabna A and Ruby John Anto |
12 |
36th Annual Conference of Indian Association for Cancer research, The 21st Century War on Cancer |
Contributed |
Amala Cancer Research Centre, Thrissur |
9-11 February 2017 |
National |
Mechanistic Evaluation and In vivo validation of tryptanthrin as a potent molecule against malignant melanoma |
13 |
International Conference on Neutraceuticals and Chronic Diseases |
Invited |
Organized by Society for neutraceuticals and Chronic diseases |
1-3 September 2017 |
International |
Mechanistic Evaluation and In vivo validation of the Molecular Mechanism of tryptanthrin as an effective therapeutic agent against malignant melanoma, Shabna A, Jayesh Antony, Vinod V, Minakshi Saikia and Ruby John Anto |
14 |
International Conference on Neutraceuticals and Chronic Diseases |
Contributed |
Organized by Society for neutraceuticals and Chronic diseases |
1-3 September 2017 |
International |
Evaluation of the chemotherapeutic and chemopreventive potential of Tryptanthrin against Non-Melanoma skin cancer, Mohan Sankar G, Jayesh Antony,Devika VS, Archana Keshavan and Ruby John Anto |
15 |
International Conference on Neutraceuticals and Chronic Diseases |
Contributed |
Organized by Society for neutraceuticals and Chronic diseases |
1-3 September 2017 |
International |
Unravelling the Molecular Events Regulating the Therapeutic Potential of Tryptanthrin in Melanoma Chemotherapy, Shabna A, Jayesh Antony, Vinod V, Minakshi Saikia,Vidya Peter and Ruby John Anto |
16 |
PRAGMA |
Invited |
Alphonsa College, Palai |
01/03/2018 |
Regional |
Drug Discovery in Cancer |
17 |
New horizons in Cancer Treatment and Prevention: From Bench to Bedside (Jointly sponsored by DST |
Contributed |
SN College, Kollam |
16th & 17th March 2018 |
National |
Isolation of an antimelanoma compound Tryptanthrin from Wrighia tinctoria |
18 |
31st Kerala Science Congress |
Contributed |
Fatima Mata National College, Kollam |
2nd February 2019 |
Regional |
Deciphering the molecular events regulated by tryptanthrin in melanoma, Shabna A, Ruby John Anto, Jayesh Antony, Vinod Vand Archana PR |
19 |
32ndKerala Science Congress |
Contributed |
Yuvakshetra Institute of Management Studies, Mundur, Palakkad |
25th-27th january 2020 |
Regional |
Intrepreting the mechanism of action of Tryptanthrin, an anticancer compound from W.tinctoria against malignant melanoma, Shabna A, Ruby John Anto, Jayesh Antony, Vinod V, |
20 |
Webinar |
Invited |
Post Graduate Department of Zoology, Deva Matha College, Kuravilangadu [Online] |
25 June 2022 |
Regional |
Sickle Cell Anaemia-Past to Present |
Honours and Awards:
Sl.No | Name of the Award | Instituted By |
---|---|---|
1 |
M R Das Career award |
For the professional achievements gained during the PhD tenure in Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 13th July 2015. |
2 |
Best Research presentation award [RGCB Students Merit Award] |
Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, November 2013 |
3 |
Best Poster Award |
International Cancer research Symposium held at Rajiv Gandhi Centre for Biotechnology, Trivandrum, December 2010 |
4 |
Junior Research Fellowship |
UGC-CSIR, December 2007 |
5 |
National Eligibility Test |
UGC-CSIR, June 2006 |
6 |
National Eligibility Test |
UGC-CSIR, June 2007 |
7 |
First rank in B.Sc. Zoology |
Mahatma Gandhi University |
8 |
Best Poster Award |
International Conference on Advances in Biological Sciences held at Kannur University, March 2012 |
9 |
Best Oral Presentation award, as co-author of the work |
32nd Kerala Science congress |
Positions held or holding if any:
Sl.No | Position | Year |
---|---|---|
1 |
Member, UG Board of Studies in Biotechnology, Mahatma Gandhi University, Kottayam |
2021 |
2 |
Research Guide in Zoology and Biotechnology, Post Graduate Department of Botany, St.Thomas College, Palai |
June 2022 |
Editorial and Referee Positions:
Sl.No | Name of the Journal | Position held |
---|---|---|
1 |
Anti-Cancer Agents in Medicinal Chemistry |
Reviewer |
2 |
Proceedings of the National Academy of Sciences, Biological Sciences (NASB) |
Reviewer |
3 |
PLOS ONE |
Reviewer |
Courses attended for Professional Developments:
Sl.No | Name of the Course | Organizing institute | Period |
---|---|---|---|
1 |
Orientation Programme |
UGC-HRDC, University of Calicut |
06-11-2019 to 26-11-22019 |
2 |
Two-week workshop on Research Methedology |
College Development Counsil, MG University, Kottayam |
03-12-2018 to 17-12-2018 |
3 |
Refresher Course in Material Science: Recombinant Memetics |
UGC-HRDC, University of Calicut |
21-10-2020 to 06-11-2020 |
4 |
ICAR sponsored Winter School on Recent Development in Taxonomic Techniques of marine Fishes for Conservation and Sustainable Fisheries Management |
ICAR- Central Marine Fisheries Research Institute, Kochi |
03-01-2022 to 23-01-2022 |